The rational design and implementation of synthetic, orthogonal mammalian communication systems has the potential to unravel fundamental design principles of mammalian cell communication circuits and offer a framework for engineering of designer cell consortia with potential applications in cell therapeutics and artificial tissue engineering. We lay here the foundations for the engineering of. Antibody-based molecular recognition plays a dominant role in the life sciences ranging from applications in diagnostics and molecular imaging to targeted drug delivery and therapy. Here we report a generic approach to introduce protease sensitivity into antibody-based targeting by taking advantage of the intrinsic ability of antibodies to engage in multivalent interactions.
AMLnZu_fFaNsBBZYXhcZK6TAgvENEPlEHpHuR9RzAeHMg=s900ckc0x00ffffffnorj
A photocrosslinkable protein G variant was used as an adapter protein to covalently and site-specifically conjugate an antibody and an Fc-fusion protein to an oligonucleotide. This modular approach enables straightforward decoration of DNA nanostructures with complex native proteins while retaining their inn 2017 Emerging Investigators Numerous biological applications, from diagnostic assays to immunotherapies, rely on the use of antibody-conjugates. The efficacy of these conjugates can be significantly influenced by the site at which Immunoglobulin G (IgG) is modified. Current methods that provide control over the conjugation site, however, suffer from a number of shortfalls and often require large investments of time and. Maarten Degreef Join now Join to view profile Sciensano The University of Glasgow Company Website Activity En daar is ie dan: de nieuwe interfederale strategie voor een globaal en geïntegreerd. 27 Nov 2020 Vol 370, Issue 6520 pp. 1034 - 1035 DOI: 10.1126/science.abb5607 Cytokines have far-reaching effects on the behavior of immune cells. Given their powerful roles, there has been a long history of trying to harness cytokines as therapeutic drugs for cancer and other diseases.
Pius XCollege Bladel worstelt met lastige leerlingen 'Andere scholieren voelen zich soms
Authors Tom F A De Greef 1 , Maarten M J Smulders , Martin Wolffs , Albert P H J Schenning , Rint P Sijbesma , E W Meijer Affiliation 1 Institute for Complex Molecular Systems and Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands. PMID: 19769364 Wouter Engelen, Lenny H. H. Meijer, Bram Somers, Tom F. A. de Greef & Maarten Merkx. Authors. Wouter Engelen. View author publications. You can also search for this author in PubMed. Maarten De Graef Ghent University | UGhent · Department of Electrical Energy, Systems and Automation Connect with experts in your field Join ResearchGate to contact this researcher and connect. Martijn van Rosmalen 1 , Brian M G Janssen 1 , Natalie M Hendrikse 1 , Ardjan J van der Linden 1 , Pascal A Pieters 1 , Dave Wanders 1 , Tom F A de Greef 1 , Maarten Merkx 2 Affiliations 1 From the Laboratory of Chemical Biology and Institute for Complex Molecular Systems (ICMS), Department of Biomedical Engineering, Eindhoven University of.
Prof. Dr. Tom de Greef Centre for Living Technologies
Pathway complexity in supramolecular polymerization. 2012 Jan 18;481 (7382):492-6. doi: 10.1038/nature10720. Self-assembly provides an attractive route to functional organic materials, with properties and hence performance depending sensitively on the organization of the molecular building blocks. Molecular organization is a direct consequence. Martijn de Greef's 43 research works with 789 citations and 5,000 reads, including: Thermal ablation of a confluent lesion in the porcine kidney with a clinically available MR-HIFU system
Freek V. de Graaf, Stef A. H. Jansen, Tobias Schnitzer, E. W. Meijer, Ghislaine Vantomme. Controlling Helical Asymmetry in Supramolecular Copolymers by In Situ Chemical Modification. Journal of the American Chemical Society 2023 , 145 (26) , 14379-14386. Neem rechtstreeks contact op met Maarten. Bekijk het profiel van Maarten de Greef op LinkedIn, de grootste professionele community ter wereld. Maarten heeft 2 functies op zijn of haar profiel. Bekijk het volledige profiel op LinkedIn om de connecties van Maarten en vacatures bij vergelijkbare bedrijven te zien.
Maarten de Leeuw LinkedIn
Tom F. A. de Greef Dr. Laboratory of Macromolecular and Organic Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven (The Netherlands), Fax: (+31) 40-245-1036. Maarten M. J. Smulders. Laboratory of Macromolecular and Organic Chemistry and Institute for Complex Molecular. Johan De Greef graduated in 2000 as a MSc in Bioscience Engineering with a major in process and environmental technology. He obtained a PhD in Chemical Engineering on the subject of flow and mass transfer in structured catalytic reactor systems.
